Synthesis of isocoumarin derivatives by copper-catalyzed addition of o-halobenzoic acids to active internal alkynes.
نویسنده
چکیده
The addition of o-halobenzoic acids to active internal alkynes proceeds efficiently in the presence of CuCl(2) as a catalyst to give the corresponding isocoumarin derivatives in moderate to good yields. This strategy offers a simple, efficient route to synthesis of the isocoumarin derivatives.
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عنوان ژورنال:
- The Journal of organic chemistry
دوره 78 4 شماره
صفحات -
تاریخ انتشار 2013